On the occasion of the release of Hunger Games, Wired website has made a list of the toughest women in movies, TV, comic books and video games. Summer Glau made the list for her role as River Tam in Firefly/Serenity, as well as Starbuck from Battlestar Galactica, Red Sonja from Marvel Comics, Xena from the tv show of the same name or Ellen Ripley from Alien to name a few.
"In Joss Whedon’s space Western TV series Firefly and its big-screen sequel Serenity, Summer Glau attracted a cult following for the character that lives on in comic-book incarnations."
Of course Summer could have had another entry as Cameron Phillips in TSCC but i guess only human were allowed on that list.
Sarah Connor also made the list.
"Linda Hamilton forever altered the muscle-to-fat ratio for machine-gun-wielding sex symbols when she played Sarah Connor in 1992’s Terminator 2: Judgment Day. More than two decades later, petite Lena Headey gave the character her own twist on TV’s Terminator: The Sarah Connor Chronicles."
You can find more examples of Summer Glau's impact on the Geek Culture in the Forum.